学術論文
2014

RNA-directed amino acid coupling as a model reaction for primitive coded translation.
Harada K, Aoyama S, Matsugami A, Kumar PK, Katahira M, Kato N, Ohkanda J.
Chembiochem. 2014 Apr 14;15(6):794-8.


2013

Stabilization of physical RAF/14-3-3 interaction by cotylenin A as treatment strategy for RAS mutant cancers.
Molzan M, Kasper S, Roglin L, Skwarczynska M, Sassa T, Inoue T, Breitenbuecher F, Ohkanda J, Kato N, Schuler M, Ottmann C.
ACS Chem Biol. 2013, 8(9), 1869-75.

A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
Anders C, Higuchi Y, Koschinsky K, Bartel M, Schumacher B, Thiel P, Nitta H, Preisig-Muller R, Schlichthorl G, Renigunta V, Ohkanda J, Daut J, Kato N, Ottmann C.
PLoS One. 2013, 8(5), e64017.

Sequence-specific and visual identification of influenza virus gene by azobenzene-tethered bis-peptide nucleic acid
K. Kaihatsu1, S. Sawada, S. Nakamura, T. Nakaya, T. Yasunaga, N. Kato
Chem Biol. 2013, 20(4), 583-93..

Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-D-xylulose 5-phosphate synthase
Daisuke Hayashi, Nobuo Kato, Tomohisa Kuzuyama, Yasuo Sato, Junko Ohkanda
Chem Commun (Camb). 2013, 49(49), 5535-7.

Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells.
Kasukabe T, Okabe-Kado J, Haranosono Y, Kato N, Honma Y.
Int J Oncol. 2013, 42(2), 767-75.

Chemical ligation of epoxide-containing fusicoccins and peptide fragments guided by 14-3-3 protein
Toshio Maki, Akie Kawamura, Nobuo Kato, Junko Ohkanda
Mol. BioSyst., 2013, in press.

Peptidomimetic modification improves cell permeation of bivalent farnesyltransferase inhibitors
Shinnosuke Machida, Mai Tsubamoto, Nobuo Kato, Kazuo Harada, Junko Ohkanda
Bioorg. Med. Chem., 2013. 2013, 9(5), 940-3.


2012

Label-free single-particle imaging of the influenza virus by objective-type total internal reflection dark-field microscopy
S. Enoki1, R. Iino, N. Morone, K. Kaihatsu, S. Sakakihara, N. Kato, H. Noji
Plos One, (2012) 7, e49208

A novel fusicoccin derivative preferentially targets hypoxic tumor cells and inhibits tumor growth in xenografts
Koshi Kawakami, Miho Hattori, Takatsugu Inoue, Yuriko Maruyama, Junko Ohkanda, Nobuo Kato, Miki Tongu,
Takaya Yamada, Miho Akimoto Keizo Takenaga, Takeshi Sassa, Junji Szumiya, Yoshio Honma
Anticancer Agents Med. Chem., 2012, 12,791-800

Protein recognition of hetero-/homoleptic ruthenium (II) tris(bipyridine)s for a-chymotrypsin and cytochrome c
Y. Yamaguchi,N. Kato,H. Azuma, T. Nagasaki, J. Ohkanda
Bioorg. Med. Chem. Lett.，22 6 2354-2358

Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate
Y. Matsumoto, K. Kaihatsu, K. Nishino, M. Ogawa, N. Kato, A. Yamaguchi
Frontiers in Antimicrobials, Resistance and Chemotherapy，3 Article 53 1-10

Recent developments in anti-influenza A virus drugs and their combination therapires.
K. Kaihatsu*. D.L. Barnard.
Frontiers in Antimicrobials, Mini-review in Organic Chemistry, (2012) 9, 3-10.

Phosphopeptide-dependent 14-3-3z fluorescence labeling by fusicoccins
M. Takahashi, A. Kawamura, N. Kato, T. Nishi, I. Hamachi, J. Ohkanda
Angew. Chem. Int. Ed.，51 2 509-512


2011

Synthesis and application of visible light sensitive azobenzene
S. Sawada, N. Kato, K. Kaihatsu
Current Pharm. Bio., 2011 Ahead of printing

Dioxygenases, Key Enzymes to Determine the Aglycon Structures of Fusicoccin and Brassicicene,
Diterpene Compounds Produced by Fungi
Y Ono., A. Minami, M. Noike, Y. Higuchi, T. Tomoyasu, T. Sassa, N. Kato, and T. Dairi
J. Am. Chem. Soc. 2011, 133, 2548-2555

Bivalent inhibitors for disrupting protein surface-substrate interactions and for dual inhibition of protein prenyltransferases
S Machida, N. Kato, K Harada, J. Ohkanda
J. Am. Chem. Soc., 2011,133, 958-963.


2009

Protein surface recognition by dendritic ruthenium(II) tris(bipyridine) complexes.
J. Ohkanda, R. Satoh, N. Kato
Chem. Comm. (Camb). 2009 , (45), :6949-51.

Inhibition of influenza virus infection by targeting genome conserved region with non-natural nucleic acid.
T. Takahashi,T. Ohzawa, S. Sawada, N. Kato, N. Goto, S. Nakamura, T. Yasunaga, K. Kaihatsu
Nucleic Acids Symp Ser (Oxf). 2009, (53), 285-6.

Regulation of duplex DNA strand displacement by visible light sensitive bis-peptide nucleic acid.
S. Sawada, I. Imada, N. Kato, K Kaihatsu.
Nucleic Acids Symp Ser (Oxf). 2009, (53), 191-2.


2008

Module assembly for protein-surface recognition: geranylgeranyltransferase I bivalent inhibitors for simultaneous targeting of interior and exterior protein surfaces.
S. Machida, K. Usuba, M.A. Blaskovich, A. Yano, K. Harada, S.M. Sebti, N. Kato, J. Ohkanda
Chemistry. 2008, 14(5), 1392-401

Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: Effect of alkyl chain length, 
S. Mori ,S Miyake, T Nakaya, N. Kato, and K. Kaihatsu
Bioorganic and Medicinal Chemistry Letters, 2008,14, 4249-4252,